Early Glaucoma Detection using LSTM-CNN integrated with Multi Class SVM

Authors

  • Vijaya Madhavi Vuppu Department of CSE, Koneru Lakshmaiah Education Foundation, Hyderabad, Telangana, India | Department of CSE, Neil Gogte Institute of Technology, Hyderabad, Telangana, India
  • P. Lalitha Surya Kumari Department of CSE, Koneru Lakshmaiah Education Foundation, Hyderabad, Telangana, India
Volume: 14 | Issue: 4 | Pages: 15645-15650 | August 2024 | https://doi.org/10.48084/etasr.7798

Abstract

Glaucoma, a progressive eye disease, is a major public concern on health due to its gradual onset and the possibility of irreversible vision loss. Early glaucoma detection is critical because it allows for timely intervention and management, lowering the risk of severe visual impairment. To address this pressing need, we present a comprehensive glaucoma detection methodology that focuses on image processing techniques and machine learning models. The initialization and preprocessing of retinal fundus images obtained from the DRIVE database is the first step in our approach. These images are resized to a standard size, grayscaled, and blurred with Gaussian blur to ensure consistency and noise reduction. Our methodology is built around feature extraction and modeling. We harness the power of deep learning, specifically Long Short-Term Memory (LSTM) and Convolutional Neural Networks (CNNs), which we integrate seamlessly with multi-class Support Vector Machines (SVMs). This synergy enables our Deep Flex SVM-MC model to capture intricate data patterns during training while also demonstrating exceptional adaptability in multi-class classification tasks. The proposed model has a glaucoma detection accuracy of 97.2%, an exceptional sensitivity of 97.53%, indicating its proficiency in correctly identifying glaucoma cases, and a specificity of 96.4%.

Keywords:

retinal fundus image, Long Short-Term Memory (LSTM), Deep Flex SVM-MC, Histogram of Oriented Gradients (HOG), glaucoma, Convolutional Neural Network (CNN), multi-class SVM, feature extraction

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References

S. P. Mariotti, Global data on visual impairments 2010. Geneva, Switzerland: World Health Organization, 2012.

J. Flammer, Glaucoma : a guide for patients, an introduction for care-providers, a quick reference. Bern, Switzerland: Hogrefe & Huber, 2003.

F. Badala, K. Nouri-Mahdavi, D. A. Raoof, N. Leeprechanon, S. K. Law, and J. Caprioli, "Optic Disk and Nerve Fiber Layer Imaging to Detect Glaucoma," American Journal of Ophthalmology, vol. 144, no. 5, pp. 724–732, Nov. 2007.

A. Osareh, M. Mirmehdi, B. Thomas, and R. Markham, "Automated identification of diabetic retinal exudates in digital colour images," British Journal of Ophthalmology, vol. 87, no. 10, pp. 1220–1223, Oct. 2003.

D. Pascolini and S. P. Mariotti, "Global estimates of visual impairment: 2010," British Journal of Ophthalmology, vol. 96, no. 5, pp. 614–618, May 2012.

S. J. K. Pedersen, Circular Hough Transform. Aalborg, Denmark: Aalborg University, 2007.

C. Sinthanayothin, J. F. Boyce, H. L. Cook, and T. H. Williamson, "Automated localisation of the optic disc, fovea, and retinal blood vessels from digital colour fundus images," British Journal of Ophthalmology, vol. 83, no. 8, pp. 902–910, Aug. 1999.

J. C. Bezdek, J. Keller, R. Krisnapuram, and N. Pal, Fuzzy Models and Algorithms for Pattern Recognition and Image Processing. Amsterdam, Netherlands: Kluwer Academic Publishers, 1999.

M. Nieves-Moreno et al., "New Normative Database of Inner Macular Layer Thickness Measured by Spectralis OCT Used as Reference Standard for Glaucoma Detection," Translational Vision Science & Technology, vol. 7, no. 1, Feb. 2018, Art. no. 20.

S. Serte and A. Serener, "A Generalized Deep Learning Model for Glaucoma Detection," in 3rd International Symposium on Multidisciplinary Studies and Innovative Technologies, Ankara, Turkey, Oct. 2019, pp. 1–5.

K. A. Thakoor, X. Li, E. Tsamis, P. Sajda, and D. C. Hood, "Enhancing the Accuracy of Glaucoma Detection from OCT Probability Maps using Convolutional Neural Networks," in 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Berlin, Germany, Jul. 2019, pp. 2036–2040.

L. Abdel-Hamid, "Glaucoma Detection from Retinal Images Using Statistical and Textural Wavelet Features," Journal of Digital Imaging, vol. 33, no. 1, pp. 151–158, Feb. 2020.

P. K. Chaudhary and R. B. Pachori, "Automatic diagnosis of glaucoma using two-dimensional Fourier-Bessel series expansion based empirical wavelet transform," Biomedical Signal Processing and Control, vol. 64, Feb. 2021, Art. no. 102237.

M. Lin et al., "Automated diagnosing primary open-angle glaucoma from fundus image by simulating human’s grading with deep learning," Scientific Reports, vol. 12, no. 1, Aug. 2022, Art. no. 14080.

H. Muhammad et al., "Hybrid Deep Learning on Single Wide-field Optical Coherence tomography Scans Accurately Classifies Glaucoma Suspects," Journal of Glaucoma, vol. 26, no. 12, pp. 1086–1094, Dec. 2017.

J. Ayub et al., "Glaucoma detection through optic disc and cup segmentation using K-mean clustering," in International Conference on Computing, Electronic and Electrical Engineering, Quetta, Pakistan, Apr. 2016, pp. 143–147.

A. Mvoulana, R. Kachouri, and M. Akil, "Fully automated method for glaucoma screening using robust optic nerve head detection and unsupervised segmentation based cup-to-disc ratio computation in retinal fundus images," Computerized Medical Imaging and Graphics, vol. 77, Oct. 2019, Art. no. 101643.

"DRIVE: Digital Retinal Images for Vessel Extraction." https://drive.grand-challenge.org/DRIVE/.

N. Bourkache, M. Laghrouch, and S. Sidhom, "Gabor Filter Algorithm for medical image processing: evolution in Big Data context," in International Multi-Conference on: "Organization of Knowledge and Advanced Technologies" (OCTA), Tunis, Tunisia, Feb. 2020, pp. 1–4.

D. Gabor, "Theory of communication," Journal of the IEEE, vol. 93, pp. 429–441, Nov. 1946.

M. Kunt and T. Ebrahimi, "Image compression by Gabor expansion," Optical Engineering, vol. 30, no. 7, pp. 873–880, Jul. 1991.

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How to Cite

[1]
V. M. Vuppu and P. L. S. Kumari, “Early Glaucoma Detection using LSTM-CNN integrated with Multi Class SVM”, Eng. Technol. Appl. Sci. Res., vol. 14, no. 4, pp. 15645–15650, Aug. 2024.

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