This is a preview and has not been published. View submission

USG Image Segmentation for Breast Cancer Detection Using the Active Contour Method

Authors

  • Herman Bedi Agtriadi School of Computer Science, BINUS University, Institut Teknologi PLN Jakarta, Indonesia
  • Edi Abdurachman School of Computer Science, Binus University Jakarta, Indonesia
  • Sani Muhammad Isa School of Computer Science, Binus University Jakarta, Indonesia
  • Boy Subirosa Sabarguna School of Computer Science, Binus University Jakarta, Indonesia
Volume: 16 | Issue: 4 | Pages: 37266-37273 | August 2026 | https://doi.org/10.48084/etasr.18899

Abstract

Breast cancer is one of the leading causes of cancer-related mortality among women. In Indonesia, it accounts for 16% of all cancer cases and 22.9% of invasive cancers in women. Ultrasonography (USG) is commonly used for breast imaging; however, its effectiveness is often limited by speckle noise, low contrast, and intensity inhomogeneity, which hinder accurate tumor segmentation. Therefore, this study aims to propose an effective segmentation framework for breast ultrasound images by integrating image enhancement and segmentation techniques. The proposed method combines Contrast Limited Adaptive Histogram Equalization (CLAHE) and contrast stretching for image enhancement, followed by Active Contour segmentation using the Chan–Vese model to accurately delineate tumor boundaries. CLAHE improves local contrast while controlling noise amplification, and contrast stretching enhances global intensity distribution to increase lesion–background separability. Experiments were conducted on 20 breast ultrasound images consisting of benign and malignant cases. The segmentation performance was evaluated using Receiver Operating Characteristic (ROC) analysis. The results show that for benign cases, the method achieved an accuracy of 92.35%, sensitivity of 80.5%, and specificity of 93.41%, whereas for malignant cases, it achieved an accuracy of 73.9%, sensitivity of 57.83%, and specificity of 73.49%. These findings indicate that the proposed approach is effective in improving segmentation performance and boundary detection in breast ultrasound images, although performance on malignant cases remains relatively lower.

Keywords:

breast cancer, segmentation, Active Contour, Receiver Operating Characteristic (ROC), MATLAB

References

[1] H. Sung et al., "Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries," CA: A Cancer Journal for Clinicians, vol. 71, no. 3, pp. 209–249, May 2021.

[2] S. M. Albeshan, S. Z. Hossain, M. G. Mackey, and P. C. Brennan, "Can Breast Self-examination and Clinical Breast Examination Along With Increasing Breast Awareness Facilitate Earlier Detection of Breast Cancer in Populations With Advanced Stages at Diagnosis?," Clinical Breast Cancer, vol. 20, no. 3, pp. 194–200, June 2020.

[3] Kriti, J. Virmani, and R. Agarwal, "A Characterization Approach for the Review of CAD Systems Designed for Breast Tumor Classification Using B-Mode Ultrasound Images," Archives of Computational Methods in Engineering, vol. 29, no. 3, pp. 1485–1523, May 2022.

[4] T. A. Sardjono, A. F. H. Chozin, and M. Nuh, "Semi-Automatic Image Segmentation on X-ray Image of Spine using Active Contour Method," JAREE (Journal on Advanced Research in Electrical Engineering), vol. 5, no. 2, pp. 89–92, Oct. 2021.

[5] R. Iacob et al., "Evaluating the Role of Breast Ultrasound in Early Detection of Breast Cancer in Low- and Middle-Income Countries: A Comprehensive Narrative Review," Bioengineering, vol. 11, no. 3, Mar. 2024, Art. no. 262.

[6] A. Nour and B. Boufama, "Hybrid deep learning and active contour approach for enhanced breast lesion segmentation and classification in mammograms," Intelligence-Based Medicine, vol. 11, Jan. 2025, Art. no. 100224.

[7] G. Qi, Z. Zhu, K. Li, and H. Xiao, "Advancements and Challenges in Medical Image Segmentation: A Comprehensive Survey," Sensors and AI, vol. 1, no. 1, pp. 3–29, Mar. 2025.

[8] M. Biesok, J. Juszczyk, and P. Badura, "Breast tumor segmentation in ultrasound using distance-adapted fuzzy connectedness, convolutional neural network, and active contour," Scientific Reports, vol. 14, no. 1, Oct. 2024, Art. no. 25859.

[9] A. Bunnell, K. Hung, J. A. Shepherd, and P. Sadowski, "BUSClean: Open-source software for breast ultrasound image pre-processing and knowledge extraction for medical AI," PLOS ONE, vol. 19, no. 12, Dec. 2024, Art. no. e0315434.

[10] A. Nugroho et al., "Automated Ultrasound Object Segmentation Using Combinatorial Active Contour Method," Jurnal Ilmu Komputer dan Informasi, vol. 17, no. 2, pp. 203–218, June 2024.

[11] X. Shen, H. Ma, R. Liu, H. Li, J. He, and X. Wu, "Lesion segmentation in breast ultrasound images using the optimized marked watershed method," BioMedical Engineering OnLine, vol. 20, no. 1, June 2021, Art. no. 57.

[12] W. El-Shafai, I. Almomani, A. Ara, and A. Alkhayer, "An optical-based encryption and authentication algorithm for color and grayscale medical images," Multimedia Tools and Applications, vol. 82, no. 15, pp. 23735–23770, June 2023.

[13] W. Liu, N. Lv, J. Wan, L. Wang, and X. Zhou, "Pixel embedding for grayscale medical image classification," Heliyon, vol. 10, no. 16, Aug. 2024, Art. no. e36191.

[14] T. Berhe and E. Diriba, "Enhancement of Mammogram Images Using Digital Image Processing Techniques for Breast Cancer Detection," Journal of Science, Technology and Arts Research, vol. 13, no. 4, pp. 188–198, Dec. 2024.

[15] T. Wang et al., "DCCE-UNet: a difference and context-aware contrast enhanced framework for ultrasound image segmentation," BMC Medical Imaging, vol. 25, no. 1, Nov. 2025, Art. no. 445.

[16] Y. Zhao, X. Shen, J. Chen, W. Qian, L. Sang, and H. Ma, "Learning active contour models based on self-attention for breast ultrasound image segmentation," Biomedical Signal Processing and Control, vol. 89, Mar. 2024, Art. no. 105816.

[17] M. Shi and I. Hussain, "Improved region-based active contour segmentation through divergence and convolution techniques," AIMS Mathematics, vol. 10, no. 1, pp. 654–671, Jan. 2025.

[18] Y. Chen, P. Ge, G. Wang, G. Weng, and H. Chen, "An overview of intelligent image segmentation using active contour models," Intelligence & Robotics, vol. 3, no. 1, pp. 23–55, Feb. 2023.

[19] M. Tamoor and I. Younas, "Automatic segmentation of medical images using a novel Harris Hawk optimization method and an active contour model," Journal of X-Ray Science and Technology, vol. 29, no. 4, pp. 721–739, July 2021.

[20] S. A. Hussein and Q. O. Mosa, "Medical Image Segmentation with active contour and optimization Techniques: Survey," Journal of Al-Qadisiyah for Computer Science and Mathematics, vol. 14, no. 4, pp. 82–89, Dec. 2022.

[21] Y. S. Malik, M. Tamoor, A. Naseer, A. Wali, and A. Khan, "Applying an adaptive Otsu-based initialization algorithm to optimize active contour models for skin lesion segmentation," Journal of X-Ray Science and Technology, vol. 30, no. 6, pp. 1169–1184, Nov. 2022.

[22] M. Mahmuddin, Z. N. M. Alqattan, N. H. Harun, and H. Harun, "An improved active contour model for food image segmentation," International Journal of Innovative Research and Scientific Studies, vol. 8, no. 4, pp. 2672–2683, July 2025.

[23] M. A. Al-Ebrahim, "Spike-Based Attention Mechanisms for Enhanced Medical Image Segmentation," Engineering, Technology & Applied Science Research, vol. 15, no. 5, pp. 28273–28285, Oct. 2025.

[24] "Breast Ultrasound Images Dataset." Kaggle. [Online]. Available: https://www.kaggle.com/datasets/aryashah2k/breast-ultrasound-images-dataset.

[25] W. Al-Dhabyani, M. Gomaa, H. Khaled, and A. Fahmy, "Dataset of breast ultrasound images," Data in Brief, vol. 28, Feb. 2020, Art. no. 104863.

[26] T. Jiang et al., "Deep learning-assisted diagnosis of benign and malignant parotid tumors based on ultrasound: a retrospective study," BMC Cancer, vol. 24, no. 1, Apr. 2024, Art. no. 510.

[27] M. M. Philip et al., "Comparison of semi-automatic and manual segmentation methods for tumor delineation on head and neck squamous cell carcinoma (HNSCC) positron emission tomography (PET) images," Physics in Medicine & Biology, vol. 69, no. 9, Apr. 2024, Art. no. 095005.

[28] S. Z. Kurdi, "Machine Learning–Based Classification Framework for Human Health Care Monitoring," International Journal of Theoretical & Applied Computational Intelligence, vol. 2026, pp. 1–15, Jan. 2026.

[29] B. Mughal, M. Sharif, N. Muhammad, and T. Saba, "A novel classification scheme to decline the mortality rate among women due to breast tumor," Microscopy Research and Technique, vol. 81, no. 2, pp. 171–180, 2018.

[30] B. Mughal, N. Muhammad, M. Sharif, A. Rehman, and T. Saba, "Removal of pectoral muscle based on topographic map and shape-shifting silhouette," BMC Cancer, vol. 18, no. 1, Aug. 2018, Art. no. 778.

[31] M. Karimi et al., "Feature Selection Methods in Big Medical Databases: A Comprehensive Survey," International Journal of Theoretical & Applied Computational Intelligence, vol. 2025, pp. 181–209, Sept. 2025.

Downloads

How to Cite

[1]
H. B. Agtriadi, E. Abdurachman, S. M. Isa, and B. S. Sabarguna, “USG Image Segmentation for Breast Cancer Detection Using the Active Contour Method”, Eng. Technol. Appl. Sci. Res., vol. 16, no. 4, pp. 37266–37273, Aug. 2026.

Metrics

Abstract Views: 21
PDF Downloads: 15

Metrics Information