An Intelligent Clinical Decision-Support Framework for the Accurate Identification and Diagnosis of Oral Potentially Malignant Disorders Using a Deep Representation Model

Samah Alzanin; Mohammed Alonazi

doi:10.48084/etasr.17472

Authors

Samah Alzanin Department of Computer Science, College of Computer Engineering and Sciences, Prince Sattam bin Abdulaziz University, Kharj, Saudi Arabia
Mohammed Alonazi Department of Information Systems, College of Computer Engineering and Sciences, Prince Sattam bin Abdulaziz University, Al-Kharj, Saudi Arabia

Volume: 16 | Issue: 2 | Pages: 33485-33491 | April 2026 | https://doi.org/10.48084/etasr.17472

Received: 11 January 2026 | Revised: 27 January 2026 | Accepted: 7 February 2026 | Online: 14 February 2026

Corresponding author: Samah Alzanin

Abstract

Clinical Decision Support Systems (CDSSs) play a crucial role in modern healthcare by enabling health professionals to efficiently analyze patient data and make accurate, evidence-based clinical decisions. In the context of CDSSs, the analysis of Oral Potentially Malignant Disorders (OPMD) has seen advances through digital technologies, as Computer-Aided Diagnosis (CAD) techniques that incorporate Artificial Intelligence (AI) and image processing play a vital role in early detection. Currently, Deep Learning (DL) in OPMD diagnosis has the capacity to handle intricate patterns, employ differences in image quality, and continuously enhance with more data. Incorporation of DL into oral healthcare not only improves diagnostic accuracy but also has the potential to streamline screening, minimize human errors, and provide earlier intervention, eventually improving patient outcomes and supporting the overall treatment of oral health conditions. This study presents an Improved Oral Potentially Malignant Disorder Diagnosis using a Stacked Sparse Autoencoder (IOPMDD-SSAE) technique to support clinical decisions in the recognition and classification of OPMD. Oral images of patients can be uploaded to a CDSS, where the IOPMDD-SSAE technique can analyze them, offering an accurate and automatic investigation. IOPMDD-SSAE uses a Wiener Filtering (WF) technique to remove noise. The complex and intrinsic features of the oral images are captured by an SE-ResNet model. Finally, OPMD detection and classification take place using a Stacked Sparse Autoencoder (SSAE). An extensive set of simulations was conducted, with the experimental results showing that IOPMDD-SSAE achieves superior detection outcomes compared to other models.

Keywords:

oral cancer, Internet of Things(IoT), Wiener filtering, computer-aided diagnosis, clinical decision support

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