An Efficient Model for Lung Cancer Detection through the Integration of Genetic Algorithm and Machine Learning
Received: 5 October 2024 | Revised: 30 October 2024 | Accepted: 3 November 2024 | Online: 11 November 2024
Corresponding author: Abdulaziz A. Alsulami
Abstract
Prompt lung cancer detection is essential for patient health. Deep Learning (DL) models have been intensively used for lung cancer screening, as they provide high accuracy in diagnoses. However, DL models require significant computational power, which may not be accessible in all settings. Conventional Machine Learning (ML) models may not produce high prediction accuracy, especially with large data. This study uses a Genetic Algorithm (GA) approach to select optimal features from lung cancer images and reduce their dimensionality. This allows conventional ML models to achieve a high prediction accuracy when classifying medical images while using lower computational power compared with DL models. The proposed model integrates GA along with ML for lung cancer detection. The experimental results show that using GA with a feed-forward neural network classifier achieved high performance, reaching 99.70% classification accuracy.
Keywords:
machine learning, image classification, genetic algorithm, deep learningDownloads
References
R. L. Siegel, A. N. Giaquinto, and A. Jemal, "Cancer statistics, 2024," CA: a cancer journal for clinicians, vol. 74, no. 1, pp. 12–49, 2024.
J. Kuon et al., "Impact of molecular alterations on quality of life and prognostic understanding over time in patients with incurable lung cancer: a multicenter, longitudinal, prospective cohort study," Supportive Care in Cancer, vol. 30, no. 4, pp. 3131–3140, Apr. 2022.
M. A. Balcı, L. M. Batrancea, Ö. Akgüller, and A. Nichita, "A Series-Based Deep Learning Approach to Lung Nodule Image Classification," Cancers, vol. 15, no. 3, Jan. 2023, Art. no. 843.
H. Zhang, Y. Peng, and Y. Guo, "Pulmonary nodules detection based on multi-scale attention networks," Scientific Reports, vol. 12, no. 1, Jan. 2022, Art. no. 1466.
Y. Li, J. Chang, and Y. Tian, "Improved cost-sensitive multikernel learning support vector machine algorithm based on particle swarm optimization in pulmonary nodule recognition," Soft Computing, vol. 26, no. 7, pp. 3369–3383, Apr. 2022.
A. Lahiri et al., "Lung cancer immunotherapy: progress, pitfalls, and promises," Molecular Cancer, vol. 22, no. 1, Feb. 2023, Art. no. 40.
J. S. Deutsch et al., "Association between pathologic response and survival after neoadjuvant therapy in lung cancer," Nature Medicine, vol. 30, no. 1, pp. 218–228, Jan. 2024.
S. Tang, T. Fan, X. Wang, C. Yu, C. Zhang, and Y. Zhou, "Cancer Immunotherapy and Medical Imaging Research Trends from 2003 to 2023: A Bibliometric Analysis," Journal of Multidisciplinary Healthcare, vol. 17, pp. 2105–2120, Dec. 2024.
W. He, B. Li, R. Liao, H. Mo, and L. Tian, "An ISHAP-based interpretation-model-guided classification method for malignant pulmonary nodule," Knowledge-Based Systems, vol. 237, Feb. 2022, Art. no. 107778.
M. A. Heuvelmans et al., "Lung cancer prediction by Deep Learning to identify benign lung nodules," Lung Cancer, vol. 154, pp. 1–4, Apr. 2021.
P. Dutande, U. Baid, and S. Talbar, "LNCDS: A 2D-3D cascaded CNN approach for lung nodule classification, detection and segmentation," Biomedical Signal Processing and Control, vol. 67, May 2021, Art. no. 102527.
B. Yin, M. Sun, J. Zhang, W. Liu, C. Liu, and Z. Wang, "AFA: adversarial frequency alignment for domain generalized lung nodule detection," Neural Computing and Applications, vol. 34, no. 10, pp. 8039–8050, May 2022.
F. Shariaty, M. Orooji, E. N. Velichko, and S. V. Zavjalov, "Texture appearance model, a new model-based segmentation paradigm, application on the segmentation of lung nodule in the CT scan of the chest," Computers in Biology and Medicine, vol. 140, Jan. 2022, Art. no. 105086.
X. Zhang, S. Li, B. Zhang, J. Dong, S. Zhao, and X. Liu, "Automatic detection and segmentation of lung nodules in different locations from CT images based on adaptive -hull algorithm and DenseNet convolutional network," International Journal of Imaging Systems and Technology, vol. 31, no. 4, pp. 1882–1893, 2021.
H. Zhang and H. Zhang, "LungSeek: 3D Selective Kernel residual network for pulmonary nodule diagnosis," The Visual Computer, vol. 39, no. 2, pp. 679–692, Feb. 2023.
L. Sun et al., "Attention-embedded complementary-stream CNN for false positive reduction in pulmonary nodule detection," Computers in Biology and Medicine, vol. 133, Jun. 2021, Art. no. 104357.
C.-F. J. Kuo, J. Barman, C. W. Hsieh, and H.-H. Hsu, "Fast fully automatic detection, classification and 3D reconstruction of pulmonary nodules in CT images by local image feature analysis," Biomedical Signal Processing and Control, vol. 68, Jul. 2021, Art. no. 102790.
K. Chen et al., "Clinical impact of a deep learning system for automated detection of missed pulmonary nodules on routine body computed tomography including the chest region," European Radiology, vol. 32, no. 5, pp. 2891–2900, May 2022.
E. J. Ostrin et al., "Contribution of a Blood-Based Protein Biomarker Panel to the Classification of Indeterminate Pulmonary Nodules," Journal of Thoracic Oncology, vol. 16, no. 2, pp. 228–236, Feb. 2021.
H. Farhat, G. E. Sakr, and R. Kilany, "Deep learning applications in pulmonary medical imaging: recent updates and insights on COVID-19," Machine Vision and Applications, vol. 31, no. 6, Jul. 2020, Art. no. 53.
A. Holzinger, K. Keiblinger, P. Holub, K. Zatloukal, and H. Müller, "AI for life: Trends in artificial intelligence for biotechnology," New Biotechnology, vol. 74, pp. 16–24, May 2023.
A. Aldoseri, K. N. Al-Khalifa, and A. M. Hamouda, "Re-Thinking Data Strategy and Integration for Artificial Intelligence: Concepts, Opportunities, and Challenges," Applied Sciences, vol. 13, no. 12, Jan. 2023, Art. no. 7082.
S. L. Goldenberg, G. Nir, and S. E. Salcudean, "A new era: artificial intelligence and machine learning in prostate cancer," Nature Reviews Urology, vol. 16, no. 7, pp. 391–403, Jul. 2019.
V. Kaul, S. Enslin, and S. A. Gross, "History of artificial intelligence in medicine," Gastrointestinal Endoscopy, vol. 92, no. 4, pp. 807–812, Oct. 2020.
A. Prelaj et al., "Machine Learning Using Real-World and Translational Data to Improve Treatment Selection for NSCLC Patients Treated with Immunotherapy," Cancers, vol. 14, no. 2, Jan. 2022, Art. no. 435.
S. T. Vemula, M. Sreevani, P. Rajarajeswari, K. Bhargavi, J. M. R. S. Tavares, and S. Alankritha, "Deep Learning Techniques for Lung Cancer Recognition," Engineering, Technology & Applied Science Research, vol. 14, no. 4, pp. 14916–14922, Aug. 2024.
B. He et al., "Predicting response to immunotherapy in advanced non-small-cell lung cancer using tumor mutational burden radiomic biomarker," Journal for Immunotherapy of Cancer, vol. 8, no. 2, Jul. 2020, Art. no. e000550.
W. Ali and F. Saeed, "Hybrid Filter and Genetic Algorithm-Based Feature Selection for Improving Cancer Classification in High-Dimensional Microarray Data," Processes, vol. 11, no. 2, Feb. 2023, Art. no. 562.
P. G. Mikhael et al., "Sybil: A Validated Deep Learning Model to Predict Future Lung Cancer Risk From a Single Low-Dose Chest Computed Tomography," Journal of Clinical Oncology, vol. 41, no. 12, pp. 2191–2200, Apr. 2023.
I. Naseer, T. Masood, S. Akram, A. Jaffar, M. Rashid, and M. Amjad Iqbal, "Lung Cancer Detection Using Modified AlexNet Architecture and Support Vector Machine," Computers, Materials & Continua, vol. 74, no. 1, pp. 2039–2054, 2023.
S. Wankhade and V. S., "A novel hybrid deep learning method for early detection of lung cancer using neural networks," Healthcare Analytics, vol. 3, Nov. 2023, Art. no. 100195.
A. Syed Musthafa, K. Sankar, T. Benil, and Y. N. Rao, "A hybrid machine learning technique for early prediction of lung nodules from medical images using a learning-based neural network classifier," Concurrency and Computation: Practice and Experience, vol. 35, no. 3, 2023, Art. no. e7488.
V. K. Gugulothu and S. Balaji, "An early prediction and classification of lung nodule diagnosis on CT images based on hybrid deep learning techniques," Multimedia Tools and Applications, May 2023.
S. Zafar, J. Ahmad, Z. Mubeen, and G. Mumtaz, "Enhanced Lung Cancer Detection and Classification with mRMR-Based Hybrid Deep Learning Model," Journal of Computing & Biomedical Informatics, vol. 7, no. 02, Sep. 2024.
M. M. Musthafa, I. Manimozhi, T. R. Mahesh, and S. Guluwadi, "Optimizing double-layered convolutional neural networks for efficient lung cancer classification through hyperparameter optimization and advanced image pre-processing techniques," BMC Medical Informatics and Decision Making, vol. 24, no. 1, May 2024, Art. no. 142.
A. Mohammed Qadir, P. Ahmed Abdalla, and D. Faiq Abd, "A Hybrid Lung Cancer Model for Diagnosis and Stage Classification from Computed Tomography Images," Iraqi Journal for Electrical and Electronic Engineering, vol. 20, no. 2, pp. 266–274, Dec. 2024.
S. Majumder, N. Gautam, A. Basu, A. Sau, Z. W. Geem, and R. Sarkar, "MENet: A Mitscherlich function based ensemble of CNN models to classify lung cancer using CT scans," PLOS ONE, vol. 19, no. 3, 2024, Art. no. e0298527.
H. F. Al-Yasriy, M. S. Al-Husieny, F. Y. Mohsen, E. A. Khalil, and Z. S. Hassan, "Diagnosis of Lung Cancer Based on CT Scans Using CNN," IOP Conference Series: Materials Science and Engineering, vol. 928, no. 2, Aug. 2020, Art. no. 022035.
H. F. Kareem, M. S. AL-Huseiny, F. Y. Mohsen, E. A. Khalil, and Z. S. Hassan, "Evaluation of SVM performance in the detection of lung cancer in marked CT scan dataset," Indonesian Journal of Electrical Engineering and Computer Science, vol. 21, no. 3, Mar. 2021, Art. no. 1731.
H. F. Al-Yasriy, "The IQ-OTH/NCCD lung cancer dataset." Kaggle, https://doi.org/10.34740/KAGGLE/DS/672399.
A. Rajab, "Genetic Algorithm-Based Multi-Hop Routing to Improve the Lifetime of Wireless Sensor Networks," Engineering, Technology & Applied Science Research, vol. 11, no. 6, pp. 7770–7775, Dec. 2021.
S. Katoch, S. S. Chauhan, and V. Kumar, "A review on genetic algorithm: past, present, and future," Multimedia Tools and Applications, vol. 80, no. 5, pp. 8091–8126, Feb. 2021.
S. Saechueng and U. Suttapakti, "Binary Count Ratio for Lung Cancer Classification in Computerized Tomography Scan Images," in 2024 International Conference on Artificial Intelligence in Information and Communication (ICAIIC), Osaka, Japan, Feb. 2024, pp. 070–074.
B. Mostafa, M. Sakr, and A. Keshk, "Employing the Capabilities of LSTM and Bi-LSTM for Lung Cancer Detection and Classification.," International Journal of Intelligent Engineering & Systems, vol. 17, no. 5, 2024.
Downloads
How to Cite
License
Copyright (c) 2024 Abdulaziz A. Alsulami
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
- Authors retain the copyright and grant the journal the right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) after its publication in ETASR with an acknowledgement of its initial publication in this journal.